Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.72 |
| ▸ | CASR | P41180 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29182072 | 0.88 | MEN1 (0.61) | EPHX2CASRCYP2C9CYP2C19MEN1 | |
| SCHEMBL5947886 | 0.86 | EPHX2 (0.63) | EPHX2CASRCYP2C9CYP2C19MEN1 | |
| SCHEMBL5948102 | 0.85 | EPHX2 (1.00) | EPHX2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL5948063 | 0.84 | EPHX2 (0.79) | EPHX2CASRCYP2C9CYP2C19MEN1 | |
| SCHEMBL4618812 | 0.84 | EPHX2 (0.79) | EPHX2CASRCYP2C9CYP2C19MEN1 | |
| SCHEMBL5947938 | 0.83 | EPHX2 (0.72) | EPHX2CASRCYP2C9CYP2C19MEN1 | |
| SCHEMBL5947967 | 0.82 | EPHX2 (0.57) | EPHX2CASRCYP2C9CYP2C19MEN1 | |
| SCHEMBL5948045 | 0.82 | EPHX2 (0.53) | EPHX2CASRCYP2C9CYP2C19MEN1 | |
| SCHEMBL11198968 | 0.82 | CASR (0.56) | EPHX2CASRCYP2C9CYP2C19MEN1 | |
| SCHEMBL5948014 | 0.81 | EPHX2 (0.53) | EPHX2CASRCYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276515-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276515-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | EPHX1, EPHX2, NCEH1 | EPHX2 2/4885CASR 4573/4885CYP2C9 477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.