Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.63 |
| ▸ | CA1 | P00915 | 9/20 | 0.63 |
| ▸ | CA2 | P00918 | 9/20 | 0.63 |
| ▸ | CA9 | Q16790 | 9/20 | 0.63 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL11794913 | 0.96 | CA12 (0.63) | CA12CA1CA2CA9DNM1 | |
| Potassium Ion SCHEMBL28590611 | 0.96 | CA12 (0.63) | CA12CA1CA2CA9DNM1 | |
| SCHEMBL16931557 | 0.96 | CA12 (0.69) | CA12CA1CA2CA9DNM1 | |
| SCHEMBL3896560 | 0.96 | CA12 (0.63) | CA12CA1CA2CA9DNM1 | |
| SCHEMBL16931560 | 0.96 | CA12 (0.63) | CA12CA1CA2CA9DNM1 | |
| SCHEMBL3896548 | 0.93 | CA12 (0.59) | CA12CA1CA2CA9DNM1 | |
| SCHEMBL16628387 | 0.86 | CA1 (0.59) | CA12CA1CA2CA9CA4 | |
| Potassium Ion SCHEMBL16628378 | 0.86 | CA12 (0.54) | CA12CA1CA2CA9DNM1 | |
| SCHEMBL16628415 | 0.86 | CA12 (0.54) | CA12CA1CA2CA9DNM1 | |
| SCHEMBL16628519 | 0.86 | CA12 (0.54) | CA12CA1CA2CA9DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142621-A1 | Bismuth dithiocarbamate compounds and uses thereof | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142621-A1 | Bismuth dithiocarbamate compounds and uses thereof | RB1, PBRM1, REL | CA12 190/4885CA1 404/4885CA2 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.