SCHEMBL5953701

SCHEMBL5953701

CCCCCCNC(=S)SC.CCCCCCNC(=S)SC.CCCCCCNC(=S)SC.[Bi]

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 10/20 0.48
CASP2 P42575 1/20 0.44
IDO1 P14902 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
NAAA Q02083 1/20 0.41
EPHX2 P34913 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1285950 0.98 EPHX1 (0.50) EPHX1CASP2IDO1ZDHHC20ZDHHC2
SCHEMBL1285963 0.96 EPHX1 (0.46) EPHX1CASP2IDO1ZDHHC20ZDHHC2
SCHEMBL1286292 0.89
SCHEMBL27914218 0.83 EPHX1 (0.48) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL28757302 0.83 EPHX1 (0.48) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL27671249 0.83 EPHX1 (0.48) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL27775479 0.83 EPHX1 (0.48) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL27428077 0.83 EPHX1 (0.48) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL27823591 0.83 EPHX1 (0.48) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL28240095 0.83 EPHX1 (0.48) EPHX1CASP2ZDHHC20ZDHHC2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060142621-A1 Bismuth dithiocarbamate compounds and uses thereof NATIONAL UNIVERSITY OF SINGAPORE (SG) 2006-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142621-A1 Bismuth dithiocarbamate compounds and uses thereof RB1, PBRM1, REL EPHX1 3581/4885CASP2 3740/4885IDO1 2357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.