Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDUA | P35475 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055465 | 0.93 | IDUA (0.48) | IDUALMNAGBA1KDM4EUSP2 | |
| Hydrochloric Acid SCHEMBL11585951 | 0.90 | IDUA (0.46) | IDUALMNAGBA1 | |
| SCHEMBL17032222 | 0.86 | — | — | |
| SCHEMBL667239 | 0.86 | — | — | |
| SCHEMBL18499992 | 0.86 | — | — | |
| SCHEMBL2369309 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL9095080 | 0.83 | IDUA (0.33) | IDUAKDM4EUSP2ESR1POLB | |
| Phosphine SCHEMBL2294350 | 0.83 | IDUA (0.33) | IDUAKDM4EUSP2ESR1POLB | |
| Water SCHEMBL3834304 | 0.83 | IDUA (0.33) | IDUAKDM4EUSP2ESR1POLB | |
| Bromide SCHEMBL11666444 | 0.83 | IDUA (0.33) | IDUAKDM4EUSP2ESR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138499-B2 | Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof | APPLERA CORPORATION (US) | 2006-11-21 | — | — | US | disclosed |
| US-20060150265-A1 | Transgenic mice containing sulfotransferase gene disruptions | ALLEN KEITH D | 2006-07-06 | — | — | US | disclosed |
| US-6967094-B2 | Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof | APPLERA CORPORATION (US) | 2005-11-22 | — | — | US | disclosed |
| US-6953681-B2 | Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof | APPLERA CORPORATION (US) | 2005-10-11 | — | — | US | disclosed |
| US-20050196802-A1 | Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof | APPLERA CORPORATION (US) | 2005-09-08 | — | — | US | disclosed |
| US-6905855-B2 | Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof | APPLERA CORPORATION (US) | 2005-06-14 | — | — | US | disclosed |
| US-20030166189-A1 | Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof | PE CORPORATION (NY) | 2003-09-04 | — | — | US | disclosed |
| EP-1304920-A2 | TRANSGENIC MICE CONTAINING TARGETED GENE DISRUPTIONS | Deltagen, Inc. (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-1278827-A2 | ISOLATED HUMAN DRUG-METABOLIZING PROTEINS, NUCLEIC ACID MOLECULES ENCODING HUMAN DRUG-METABOLIZING PROTEINS, AND USES THEREOF | PE Corporation (NY) (US) | 2003-01-29 | — | — | EP | disclosed |
| US-20030008354-A1 | Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof | PE CORPORATION (NY) (US) | 2003-01-09 | — | — | US | disclosed |
| US-20020022255-A1 | Transgenic mice containing sulfotransferase gene disruptions | DELTAGEN, INC. | 2002-02-21 | — | — | US | disclosed |
| WO-2001072977-A2 | ISOLATED HUMAN DRUG-METABOLIZING PROTEINS, NUCLEIC ACID MOLECULES ENCODING HUMAN DRUG-METABOLIZING PROTEINS, AND USES THEREOF | PE CORPORATION (NY) (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001067855-A2 | TRANSGENIC MICE CONTAINING TARGETED GENE DISRUPTIONS | DELTAGEN, INC. (US) | 2001-09-20 | — | — | WO | disclosed |
| US-6132913-A | Photoreceptor overcoatings containing hydroxy functionalized aromatic diamine, hydroxy functionalized triarylamine and crosslinked acrylated polyamide | XEROX CORPORATION (US) | 2000-10-17 | — | — | US | disclosed |
| US-6107439-A | MIXTURE COMPRISING AN OXIDIZED AND NON-OXIDIZED HOLE TRANSPRTING HYDROXY-FUNCTIONAL ARYL AMINE IN A CROSSLINKED POLYAMIDE MATRIX WHEREBY THE OXIDATION AND CROSSLINKING HAS BEEN SIMULTANEOUSLY CAUSED BY AN ACID | XEROX CORPORATION (US) | 2000-08-22 | — | — | US | disclosed |
| US-6103436-A | A PHOTOCONDUCTIVE LAYER COMPRISING A HYDROXY FUNCTIONALIZED AROMATIC DIAMINE AND A HYDROXY FUNCTIONALIZED TRIARYLAMINE AND A CROSSLINKED POLYAMIDE MATRIX | XEROX CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
| US-5976744-A | ELECTROPHOTOGRAPHIC IMAGING MEMBER | XEROX CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| US-5744355-A | GENETIC ENGINEERING | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1998-04-28 | — | — | US | disclosed |
| US-5118849-A | Arylamines intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-5039334-A | Herbicidal and plant growth-regulating substituted N-aryl nitrogen heterocycles | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-13 | — | — | US | disclosed |