Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 15/20 | 0.65 |
| ▸ | NR1H2 | P55055 | 13/20 | 0.65 |
| ▸ | PPARG | P37231 | 9/20 | 0.64 |
| ▸ | PPARA | Q07869 | 7/20 | 0.64 |
| ▸ | PPARD | Q03181 | 6/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953868 | 0.88 | NR1H3 (0.69) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL5807237 | 0.84 | GRM2 (0.56) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL6371470 | 0.83 | NR1H3 (0.75) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL6349256 | 0.83 | NR1H3 (0.70) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL6168918 | 0.83 | NR1H3 (0.68) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL6099414 | 0.82 | NR1H3 (0.69) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL1400270 | 0.82 | NR1H3 (0.66) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL5953874 | 0.81 | NR1H3 (0.66) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL6366557 | 0.81 | NR1H3 (0.67) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL6175211 | 0.81 | NR1H3 (0.66) | NR1H3NR1H2PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060020036-A1 | Methods and compositions to promote bone homestasis | GALAPAGOS N.V. (BE) | 2006-01-26 | — | — | US | disclosed |