SCHEMBL5953970

SCHEMBL5953970

CN(C)CCC1(c2ccccc2)Cc2ccccc2C(=O)O1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5954192 0.99 UTS2R (0.84) UTS2R
SCHEMBL5954681 0.91 UTS2R (0.80) UTS2R
Hydrochloric Acid SCHEMBL5954576 0.90 UTS2R (0.82) UTS2R
SCHEMBL4794741 0.90 UTS2R (1.00) UTS2R
SCHEMBL11582318 0.90 UTS2R (0.78) UTS2R
SCHEMBL5954022 0.89 UTS2R (1.00) UTS2R
Hydrochloric Acid SCHEMBL5954508 0.88 UTS2R (0.98) UTS2R
SCHEMBL5954623 0.88 UTS2R (0.81) UTS2R
SCHEMBL11582306 0.87 UTS2R (0.63) UTS2R
SCHEMBL5954186 0.87 UTS2R (0.76) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060058374-A1 Urotensin II receptor agents ACADIA PHARMACEUTICALS INC. 2006-03-16 US claimed
US-20040077529-A1 Urotensin II receptor agents ACADIA PHARMACEUTICALS, INC. 2004-04-22 US claimed
WO-2003104216-A1 UROTENSIN II RECEPTOR MODULATORS ACADIA PHARMACEUTICALS INC. (US) 2003-12-18 WO claimed
US-20060058374-A1 Urotensin II receptor agents ACADIA PHARMACEUTICALS INC. 2006-03-16 US disclosed
US-20040077529-A1 Urotensin II receptor agents ACADIA PHARMACEUTICALS, INC. 2004-04-22 US disclosed
WO-2003104216-A1 UROTENSIN II RECEPTOR MODULATORS ACADIA PHARMACEUTICALS INC. (US) 2003-12-18 WO disclosed
US-4083997-A ANTIDEPRESSANTS SANDOZ, INC. (US) 1978-04-11 US disclosed
US-3994961-A ANTIDEPRESSANTS SANDOZ, INC. (US) 1976-11-30 US disclosed
US-3880885-A Tertiary aminoethyl isochromans and isocoumarins SANDOZ AG 1975-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077529-A1 Urotensin II receptor agents UTS2R, PLAUR, GPR17 UTS2R 1/4885
US-20060058374-A1 Urotensin II receptor agents UTS2R, PLAUR, SCTR UTS2R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.