⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylmalonic Acid SCHEMBL27881917 | 0.81 | TP53 (0.57) | — | |
| Methylmalonic Acid SCHEMBL27766 | 0.81 | — | — | |
| Methylmalonic Acid SCHEMBL29018402 | 0.77 | — | — | |
| Methylmalonic Acid SCHEMBL10461696 | 0.77 | — | — | |
| Methylmalonic Acid SCHEMBL29092066 | 0.77 | — | — | |
| Methylmalonic Acid SCHEMBL29060551 | 0.77 | — | — | |
| Methylmalonic Acid SCHEMBL5874913 | 0.77 | — | — | |
| Methylmalonic Acid SCHEMBL17818678 | 0.77 | — | — | |
| Methylmalonic Acid SCHEMBL105829 | 0.77 | — | — | |
| Methylmalonic Acid SCHEMBL11586861 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120358-A1 | OLIGOMER-NITROGENOUS BASE CONJUGATES | NEKTAR THERAPEUTICS (US) | 2009-10-01 | — | — | WO | claimed |
| US-5589315-A | SHELF LIFE, SCREEN PRINTING | TOYO GOSEI KOGYO CO., LTD. (JP) | 1996-12-31 | — | — | US | claimed |
| US-5430130-A | Photosensitive polyfunctional aromatic diazo compounds useful in photosensitive compositions | TOYO GOSEI KOGYO CO., LTD. (JP) | 1995-07-04 | — | — | US | claimed |
| EP-0378706-B1 | 5-SUBSTITUTED URIDINE DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION | TAIHO PHARMACEUTICAL CO LTD (JP) | 1994-12-28 | — | — | EP | claimed |
| US-5196437-A | Macrolide | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1993-03-23 | — | — | US | claimed |
| EP-0378706-A1 | 5-SUBSTITUTED URIDINE DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1990-07-25 | — | — | EP | claimed |
| EP-0158847-B1 | ANTIVIRAL PURINE DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-04-20 | — | — | EP | claimed |
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | claimed |
| EP-0158847-A1 | Antiviral purine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-10-23 | — | — | EP | claimed |
| EP-0108285-A2 | Antiviral purine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-16 | — | — | EP | claimed |
| EP-0095813-A2 | Penetrating topical pharmaceutical compositions containing 9-(2-hydroxyethoxymethyl) guanine | THE PROCTER & GAMBLE COMPANY (US) | 1983-12-07 | — | — | EP | claimed |
| US-4360522-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-11-23 | — | — | US | claimed |
| US-4199574-A | Methods and compositions for treating viral infections and guanine acyclic nucleosides | BURROUGHS WELLCOME CO. (US) | 1980-04-22 | — | — | US | claimed |
| JP-7206671-A | — | — | None | — | — | JP | disclosed |
| JP-59167564-A | — | — | None | — | — | JP | disclosed |
| EP-3438105-B1 | DIARYL- -LACTAM COMPOUND AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | UNIV FUDAN (CN) | 2022-01-05 | — | — | EP | disclosed |
| US-4294831-A | ANTIVIRAL ACTIVITY | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |
| US-4287188-A | PARTICULARLY 9-(2-HYDROXYETHOXYMETHYL) GUANINE MONOPHOSPHATE AND SALTS, USEFUL AS ANTIVIRIAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1981-09-01 | — | — | US | disclosed |
| US-4199574-A | Methods and compositions for treating viral infections and guanine acyclic nucleosides | BURROUGHS WELLCOME CO. (US) | 1980-04-22 | — | — | US | disclosed |
| US-4146715-A | ANTIVIRAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1979-03-27 | — | — | US | disclosed |