Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76669 | 0.89 | F10 (0.57) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL76587 | 0.89 | F10 (0.57) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL76586 | 0.89 | F10 (0.57) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5956859 | 0.88 | F10 (0.57) | MEN1KMT2ACYP2C9CYP2C19TSHR | |
| SCHEMBL5956956 | 0.88 | F10 (0.61) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL76844 | 0.86 | F10 (0.56) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL76845 | 0.86 | F10 (0.56) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5956913 | 0.86 | F10 (0.54) | MEN1KMT2ATSHRF10 | |
| SCHEMBL4450787 | 0.85 | F10 (0.50) | F10 | |
| SCHEMBL5956960 | 0.84 | F10 (0.65) | MEN1KMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633346-B1 | PYRROLIDIN-1, 2- DICARBOXYLIC ACID- 1- (4- ETHINYL- PHENYL) - AMID|- 2- (PHENYL)- AMID| DERIVATIVE AS INHIBITORS OF COAGULATION FACTOR XA AND VIIA FOR THE TREATMENT OF THROMBOSIS | MERCK PATENT GMBH (DE) | 2006-08-23 | — | — | EP | claimed |