Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.67 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956932 | 0.94 | F10 (0.58) | F10MTOR | |
| SCHEMBL5956894 | 0.94 | F10 (0.58) | F10MTOR | |
| SCHEMBL5956908 | 0.93 | F10 (0.57) | F10MTOR | |
| SCHEMBL5956904 | 0.92 | F10 (0.56) | F10MTOR | |
| SCHEMBL5956916 | 0.91 | F10 (0.55) | F10MTOR | |
| SCHEMBL76643 | 0.91 | F10 (0.82) | F10 | |
| SCHEMBL5956909 | 0.91 | F10 (0.81) | F10MTORMAPT | |
| SCHEMBL5956931 | 0.91 | F10 (0.81) | F10MTORMAPT | |
| SCHEMBL5956912 | 0.90 | F10 (0.54) | F10MTOR | |
| SCHEMBL5956997 | 0.89 | F10 (0.65) | F10MTORMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633346-B1 | PYRROLIDIN-1, 2- DICARBOXYLIC ACID- 1- (4- ETHINYL- PHENYL) - AMID|- 2- (PHENYL)- AMID| DERIVATIVE AS INHIBITORS OF COAGULATION FACTOR XA AND VIIA FOR THE TREATMENT OF THROMBOSIS | MERCK PATENT GMBH (DE) | 2006-08-23 | — | — | EP | claimed |