Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956870 | 0.92 | F10 (0.55) | F10PTGS2 | |
| SCHEMBL5956946 | 0.91 | F10 (0.67) | F10MAPT | |
| SCHEMBL5956912 | 0.91 | F10 (0.54) | F10 | |
| SCHEMBL5956909 | 0.89 | F10 (0.81) | F10MAPT | |
| SCHEMBL5956931 | 0.89 | F10 (0.81) | F10MAPT | |
| SCHEMBL5956918 | 0.87 | F10 (0.68) | F10MAPT | |
| SCHEMBL5956921 | 0.87 | F10 (0.68) | F10MAPT | |
| SCHEMBL5956981 | 0.86 | F10 (0.79) | F10MAPT | |
| SCHEMBL5956955 | 0.86 | F10 (0.69) | F10MAPT | |
| SCHEMBL5956901 | 0.85 | F10 (0.68) | F10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633346-B1 | PYRROLIDIN-1, 2- DICARBOXYLIC ACID- 1- (4- ETHINYL- PHENYL) - AMID|- 2- (PHENYL)- AMID| DERIVATIVE AS INHIBITORS OF COAGULATION FACTOR XA AND VIIA FOR THE TREATMENT OF THROMBOSIS | MERCK PATENT GMBH (DE) | 2006-08-23 | — | — | EP | claimed |