Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15233152 | 0.84 | P2RY12 (0.45) | P2RY12GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL1548057 | 0.83 | P2RY12 (0.45) | P2RY12GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL1548180 | 0.82 | P2RY12 (0.47) | P2RY12GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL1548537 | 0.81 | PPARG (0.49) | P2RY12GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL2580210 | 0.81 | P2RY12 (0.51) | P2RY12GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL9922813 | 0.80 | P2RY12 (0.69) | P2RY12GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL2590531 | 0.79 | P2RY12 (0.51) | P2RY12GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL14417200 | 0.79 | GAA (0.52) | P2RY12GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL1548182 | 0.78 | P2RY12 (0.49) | P2RY12GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL1548876 | 0.78 | PPARG (0.57) | P2RY12GAANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412364-B1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARM INC (US) | 2006-09-13 | — | — | EP | disclosed |