Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.53 |
| ▸ | HNF4A | P41235 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | SELL | P14151 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23985865 | 1.00 | PIM1 (0.55) | PIM1PTPN1HNF4APTPN6TRPA1 | |
| SCHEMBL7709310 | 0.86 | PTPN1 (0.57) | PIM1PTPN1HNF4APTPN6TRPA1 | |
| SCHEMBL22887320 | 0.86 | PTPN1 (0.57) | PIM1PTPN1HNF4APTPN6TRPA1 | |
| SCHEMBL29030432 | 0.85 | PIM1 (0.51) | PIM1PTPN1HNF4APTPN6TRPA1 | |
| SCHEMBL5960456 | 0.82 | CYP1A2 (0.49) | TRPA1CYP1B1ABCG2 | |
| SCHEMBL29030424 | 0.81 | PIM1 (0.48) | PIM1PTPN1HNF4APTPN6TRPA1 | |
| SCHEMBL29030433 | 0.79 | PIM1 (0.46) | PIM1PTPN1HNF4APTPN6TRPA1 | |
| SCHEMBL4619025 | 0.79 | PTPN1 (0.49) | PIM1PTPN1HNF4APTPN6TRPA1 | |
| SCHEMBL27590273 | 0.79 | PTPN1 (0.49) | PIM1PTPN1HNF4APTPN6TRPA1 | |
| SCHEMBL2291774 | 0.77 | GRIK1 (0.58) | PTPN1HNF4APTPN6TRPA1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006004722-A2 | COMPOSITIONS AND METHODS FOR SELECTIVELY ACTIVATING HUMAN SIRTUINS | BIOMOL RESEARCH LABORATORIES, INC. (US) | 2006-01-12 | — | — | WO | claimed |
| WO-2006004722-A2 | COMPOSITIONS AND METHODS FOR SELECTIVELY ACTIVATING HUMAN SIRTUINS | BIOMOL RESEARCH LABORATORIES, INC. (US) | 2006-01-12 | — | — | WO | disclosed |