Sugi Predict

Sugi Predict / Compounds / SCHEMBL5961560

SCHEMBL5961560

SCHEMBL5961560

Cc1cccc(C(=O)Nc2ccc3c(c2)C[C@H](NC(=O)O)C3)c1-c1ccc(C(F)(F)F)cc1

nearest known ligand 0.85

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ SMO Q99835 13/20 0.85
▸ MTTP P55157 12/20 0.85
▸ APOB P04114 9/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13591618 0.94 SMO (0.82) SMOMTTPAPOB
SCHEMBL7038523 0.92 MTTP (1.00) SMOMTTPAPOB
SCHEMBL10205353 0.92 MTTP (1.00) SMOMTTPAPOB
SCHEMBL4785948 0.92 MTTP (1.00) SMOMTTPAPOB
SCHEMBL7035865 0.91 SMO (0.79) SMOMTTPAPOB
SCHEMBL13591616 0.91 SMO (1.00) SMOMTTPAPOB
SCHEMBL6196022 0.90 MTTP (0.87) SMOMTTPAPOB
SCHEMBL13591624 0.89 MTTP (0.85) SMOMTTPAPOB
SCHEMBL6196040 0.89 SMO (0.78) SMOMTTPAPOB
SCHEMBL6198990 0.89 SMO (0.78) SMOMTTPAPOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8486447-B2 Pharmaceutical formulation NOVARTIS AG (CH) 2013-07-16 — — US disclosed
US-20060269608-A1 Pharmaceutical formulation NOVARTIS AG (CH) 2006-11-30 — — US disclosed
EP-1594468-A2 PROCESS FOR PREPARING A SOLID DISPERSION PHARMACEUTICAL PRODUCT Novartis AG (CH) 2005-11-16 — — EP disclosed
WO-2004069138-A2 PHARMACEUTICAL FORMULATION NOVARTIS AG (CH) 2004-08-19 — — WO disclosed