Glycine

Glycine

SCHEMBL5961782

NCC(=O)O.NCC(=O)[O-].[Na+]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLRA1 P23415 1/20 0.67
SLC6A9 P48067 1/20 0.67
OR51E2 Q9H255 1/20 0.67
CA4 P22748 4/20 0.44
CASP1 P29466 1/20 0.42
GABRR1 P24046 4/20 0.41
BLM P54132 3/20 0.37
KMT2A Q03164 2/20 0.37
LDHA P00338 2/20 0.37
MEN1 O00255 1/20 0.37
HDAC3 O15379 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
FFAR3 O14843 1/20 0.36
GABRR3 A8MPY1 1/20 0.36
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
GABBR2 O75899 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL6258845 1.00 GLRA1 (0.67) GLRA1SLC6A9OR51E2CA4CASP1
Glycine SCHEMBL8135417 0.97 GLRA1 (0.62) GLRA1SLC6A9OR51E2CA4CASP1
Glycine SCHEMBL29794412 0.93 GLRA1 (0.67) GLRA1SLC6A9OR51E2CA4CASP1
Glycine SCHEMBL30359133 0.93 GLRA1 (0.67) GLRA1SLC6A9OR51E2CA4CASP1
Glycine SCHEMBL29283480 0.93 GLRA1 (0.67) GLRA1SLC6A9OR51E2CA4CASP1
Glycine SCHEMBL713242 0.90 GLRA1 (0.62) GLRA1SLC6A9OR51E2CA4CASP1
Glycine SCHEMBL7163617 0.90 GLRA1 (0.50) GLRA1SLC6A9OR51E2CA4CASP1
Glycine SCHEMBL978831 0.90 GLRA1 (0.71) GLRA1SLC6A9OR51E2CA4CASP1
Glycine SCHEMBL16600 0.90 GLRA1 (0.71) GLRA1SLC6A9OR51E2CA4CASP1
Glycine SCHEMBL978830 0.90 GLRA1 (0.71) GLRA1SLC6A9OR51E2CA4CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114797418-B Novel process for deep dedusting, desulfurization and denitrification of flue gas and efficient energy-saving equipment system 北京紫光英力化工技术有限公司 2024-06-04 CN claimed
CN-114797418-A Novel flue gas deep dust removal, desulfurization and denitrification process and efficient energy-saving equipment system 北京紫光英力化工技术有限公司 2022-07-29 CN claimed
CN-114797418-B Novel process for deep dedusting, desulfurization and denitrification of flue gas and efficient energy-saving equipment system 北京紫光英力化工技术有限公司 2024-06-04 CN disclosed
CN-113956171-B Continuous flow synthesis process of N-hydroxymethyl sodium glycine 广东派特埃尔生物科技有限公司 2023-12-15 CN disclosed
CN-114797418-A Novel flue gas deep dust removal, desulfurization and denitrification process and efficient energy-saving equipment system 北京紫光英力化工技术有限公司 2022-07-29 CN disclosed
CN-114657567-B Corrosion inhibitor and preparation method and application thereof 河北省科学院能源研究所 2022-07-29 CN disclosed
CN-114657567-A Corrosion inhibitor and preparation method and application thereof 河北省科学院能源研究所 2022-06-24 CN disclosed
CN-113956171-A Continuous flow synthesis process of N-hydroxymethyl sodium glycinate 广东派特埃尔生物科技有限公司 2022-01-21 CN disclosed
CN-111479826-A Anti- α synuclein antibody UCB生物制药有限责任公司 2020-07-31 CN disclosed
CN-105491997-B Sublingual and buccal film compositions 阿奎蒂夫疗法公司 2019-12-17 CN disclosed
US-20170296482-A1 SUBLINGUAL AND BUCCAL FILM COMPOSITIONS MONOSOL RX, INC. 2017-10-19 US disclosed
US-5480643-A Stable antimicrobial dialdehyde composition and methods of use ECOLAB INC. (US) 1996-01-02 US disclosed
WO-1995001724-A1 STABLE ANTIMICROBIAL DIALDEHYDE COMPOSITION AND METHODS OF USE ECOLAB INC. (US) 1995-01-19 WO disclosed
EP-0609221-A1 ANTIMICROBIAL DIALDEHYDE COMPOSITION AND METHODS OF USE. ECOLAB INC (US) 1994-08-10 EP disclosed
WO-1993007747-A1 ANTIMICROBIAL DIALDEHYDE COMPOSITION AND METHODS OF USE ECOLAB, INC. (US) 1993-04-29 WO disclosed
US-5158778-A Antiseptics ECOLAB INC. (US) 1992-10-27 US disclosed
WO-1990010700-A1 MODIFIED ANTIBODIES CELLTECH LIMITED (GB) 1990-09-20 WO disclosed
EP-0388151-A1 Modified antibodies CELLTECH LIMITED (GB) 1990-09-19 EP disclosed
EP-0124018-B1 PHARMACEUTICAL PREPARATION CONTAINING PURIFIED FIBRONECTIN Armour Pharmaceutical Company (US) 1987-11-25 EP disclosed
EP-0124018-A1 Pharmaceutical preparation containing purified fibronectin Armour Pharmaceutical Company (US) 1984-11-07 EP disclosed