Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 17/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469975 | 0.89 | HRH3 (0.76) | HRH3KCNH2ADRA1A | |
| SCHEMBL4469847 | 0.89 | HRH3 (0.77) | HRH3KCNH2ADRA1A | |
| SCHEMBL4471134 | 0.89 | HRH3 (0.77) | HRH3KCNH2ADRA1A | |
| SCHEMBL4486556 | 0.87 | HRH3 (0.81) | HRH3KCNH2ADRA1A | |
| SCHEMBL4465733 | 0.83 | HRH3 (0.71) | HRH3KCNH2ADRA1A | |
| SCHEMBL4565297 | 0.82 | HRH3 (0.57) | HRH3KCNH2ADRA1A | |
| SCHEMBL15555742 | 0.82 | HRH3 (0.76) | HRH3KCNH2ADRA1A | |
| SCHEMBL4480853 | 0.82 | HRH3 (0.62) | HRH3KCNH2ADRA1A | |
| SCHEMBL4462601 | 0.81 | HRH3 (0.77) | HRH3KCNH2ADRA1A | |
| SCHEMBL4463008 | 0.81 | HRH3 (0.77) | HRH3KCNH2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1717230-B1 | FUSED-RING 4-OXOPYRIMIDINE DERIVATIVE | MSD KK (JP) | 2014-08-06 | — | — | EP | disclosed |
| EP-1717230-A1 | FUSED-RING 4-OXOPYRIMIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-02 | — | — | EP | disclosed |