SCHEMBL5962266

SCHEMBL5962266

Cc1nc2ccccc2c(=O)n1-c1ccc(OC2CCCN(C3CCCC3)CC2)cc1.Cc1nc2ccccc2c(=O)n1-c1ccc(OC2CCN(C3CCC3)C2)cc1

nearest known ligand 0.91

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 20/20 0.91
KCNH2 Q12809 6/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4475188 0.95 HRH3 (1.00) HRH3KCNH2
SCHEMBL4472514 0.95 HRH3 (1.00) HRH3KCNH2
SCHEMBL4468313 0.94 HRH3 (1.00) HRH3KCNH2
SCHEMBL4466742 0.94 HRH3 (1.00) HRH3KCNH2
SCHEMBL4467636 0.93 HRH3 (1.00) HRH3KCNH2
SCHEMBL4472893 0.93 HRH3 (1.00) HRH3KCNH2
SCHEMBL4481610 0.92 HRH3 (1.00) HRH3KCNH2
SCHEMBL23565971 0.90 HRH3 (0.94) HRH3KCNH2
SCHEMBL4465768 0.88 HRH3 (1.00) HRH3KCNH2
SCHEMBL4465772 0.88 HRH3 (1.00) HRH3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1717230-A1 FUSED-RING 4-OXOPYRIMIDINE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-11-02 EP claimed
EP-1717230-A1 FUSED-RING 4-OXOPYRIMIDINE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-11-02 EP disclosed