Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 18/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 4/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23491959 | 0.90 | MCL1 (0.51) | MCL1BCL2 | |
| SCHEMBL1448652 | 0.90 | MCL1 (0.51) | MCL1BCL2 | |
| SCHEMBL12742659 | 0.90 | MCL1 (0.51) | MCL1BCL2 | |
| SCHEMBL6974007 | 0.90 | MCL1 (0.51) | MCL1BCL2 | |
| SCHEMBL23491353 | 0.87 | MCL1 (0.54) | MCL1BCL2BCL2L1 | |
| SCHEMBL15888149 | 0.86 | MCL1 (0.49) | MCL1BCL2 | |
| SCHEMBL8999703 | 0.85 | MCL1 (0.52) | MCL1BCL2BCL2L1 | |
| SCHEMBL8999696 | 0.85 | MCL1 (0.52) | MCL1BCL2BCL2L1 | |
| SCHEMBL6847022 | 0.85 | MCL1 (0.53) | MCL1BCL2BCL2L1 | |
| SCHEMBL4313540 | 0.85 | MCL1 (0.53) | MCL1BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122521-B2 | COMPRISING TRIPEPTIDE UNIT OF THE FORMULA (flp-Yaa-Gly)N, WHERE Yaa IS ANY AMINO ACID, FLP IS 4(R)-FLUORO-L-PROLINE, AND N IS AT LEAST 3; INCREASED STABILITY; STRONGER TRIPLE HELIX THAN NATIVE COLLAGEN; FOR USE SUCH AS IN ARTIFICIAL SKIN | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-10-17 | — | — | US | disclosed |
| US-20050004032-A1 | Collagen mimics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-01-06 | — | — | US | disclosed |