⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL1337001 | 0.97 | TSHR (0.48) | — | |
| Hydrochloric Acid SCHEMBL12474495 | 0.95 | TSHR (0.46) | — | |
| Water SCHEMBL19410621 | 0.78 | TSHR (0.63) | — | |
| Water SCHEMBL27896186 | 0.78 | TSHR (0.63) | — | |
| SCHEMBL29352197 | 0.78 | TSHR (0.63) | — | |
| SCHEMBL57480 | 0.78 | TSHR (0.63) | — | |
| SCHEMBL2818597 | 0.78 | TSHR (0.63) | — | |
| SCHEMBL6155970 | 0.77 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL10899986 | 0.76 | TSHR (0.60) | — | |
| SCHEMBL3959857 | 0.76 | TSHR (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9789086-B1 | N-(5-arylamido-2-methylphenyl)-5-methylisooxazole-4-carboxamide deravative, pharmaceutical acceptable salt thereof, method for preparation therof and FMS kinase inhibitor comprising the same as anactive ingredient | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) | 2017-10-17 | — | — | US | claimed |
| US-20170273947-A1 | N-(5-ARYLAMIDO-2-METHYLPHENYL)-5-METHYLISOOXAZOLE-4-CARBOXAMIDE DERAVATIVE, PHARMACEUTICAL ACCEPTABLE SALT THEREOF, METHOD FOR PREPARATION THEROF AND FMS KINASE INHIBITOR COMPRISING THE SAME AS ANACTIVE INGREDIENT | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) | 2017-09-28 | — | — | US | claimed |
| US-20140221631-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | US | claimed |
| US-8722917-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2014-05-13 | — | — | US | claimed |
| US-20120289686-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2012-11-15 | — | — | US | claimed |
| EP-1976536-A2 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2008-10-08 | — | — | EP | claimed |
| WO-2007078340-A2 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2007-07-12 | — | — | WO | claimed |
| US-20070155699-A1 | Boron-containing small molecules | ANACOR PHARMACEUTICALS (US) | 2007-07-05 | — | — | US | claimed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | claimed |
| EP-0741129-B1 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS (JP) | 1999-06-09 | — | — | EP | claimed |
| US-5756806-A | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-05-26 | — | — | US | claimed |
| US-5679827-A | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-10-21 | — | — | US | claimed |
| EP-0741129-A2 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-11-06 | — | — | EP | claimed |
| EP-0303573-B1 | PYRROLIDINE-2,5 DIONES AND 4,5,6,7-TETRAHYDROISO-INDOLE-1,3 DIONES | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | claimed |
| EP-0303573-A1 | Pyrrolidine-2,5 diones and 4,5,6,7-tetrahydroiso-indole-1,3 diones | CIBA-GEIGY AG (CH) | 1989-02-15 | — | — | EP | claimed |
| EP-0260228-A2 | N-phenyl-malein imides and N-phenyl-succinimides with a herbicidal and a plant growth regulation activity | CIBA-GEIGY AG (CH) | 1988-03-16 | — | — | EP | claimed |
| JP-8291134-A | — | — | None | — | — | JP | disclosed |
| EP-3605160-B1 | COLOR COMPOSITION FOR SOLID-STATE IMAGING ELEMENT | TOPPAN PRINTING CO LTD (JP) | 2023-08-02 | — | — | EP | disclosed |
| EP-0007211-A1 | Derivatives of N-trifluoroacetyl-N-phosphonomethylglycinates and the herbicidal use thereof | MONSANTO COMPANY (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4180394-A | Derivatives of N-trifluoroacetyl-N-phosphonomethylglycinates and the herbicidal use thereof | MONSANTO COMPANY (US) | 1979-12-25 | — | — | US | disclosed |