⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583649 | 1.00 | — | — | |
| SCHEMBL6476990 | 1.00 | — | — | |
| Water SCHEMBL6244435 | 0.98 | — | — | |
| SCHEMBL992260 | 0.98 | — | — | |
| SCHEMBL361549 | 0.92 | — | — | |
| SCHEMBL646408 | 0.92 | EPHX1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL3021166 | 0.90 | — | — | |
| SCHEMBL27510109 | 0.88 | EPHX1 (0.39) | — | |
| Proline SCHEMBL8381835 | 0.86 | — | — | |
| SCHEMBL6360303 | 0.86 | CHRM2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12234225-B2 | IL-17 ligands and uses thereof | DICE ALPHA, INC. (US) | 2025-02-25 | — | — | US | disclosed |
| CN-113874080-B | IL-17A modulators and uses thereof | 戴斯阿尔法公司 | 2024-09-27 | — | — | CN | disclosed |
| US-20230053746-A1 | IL-17 LIGANDS AND USES THEREOF | DICE MOLECULES SV, INC. | 2023-02-23 | — | — | US | disclosed |
| US-11447468-B2 | IL-17 ligands and uses thereof | DICE ALPHA, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| CN-113874080-A | IL-17A modulators and uses thereof | 戴斯阿尔法公司 | 2021-12-31 | — | — | CN | disclosed |
| US-20200247785-A1 | IL-17 Ligands And Uses Thereof | DICE MOLECULES SV, INC. | 2020-08-06 | — | — | US | disclosed |
| US-7071168-B2 | Anti-cancer compounds and methods related thereto | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2006-07-04 | — | — | US | disclosed |
| US-20020183252-A1 | Anti-cancer compounds and methods related thereto | STEWART JOHN M (US) | 2002-12-05 | — | — | US | disclosed |
| US-6388054-B1 | AMINO ACID SEQUENCES OF ANTITUMOR AGENTS AND APOPTOSIS AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-05-14 | — | — | US | disclosed |
| WO-2000011022-A1 | ANTI-CANCER COMPOUNDS AND METHODS RELATED THERETO | STEWART JOHN M (US) | 2000-03-02 | — | — | WO | disclosed |