⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2340 | 1.00 | — | — | |
| SCHEMBL2341 | 1.00 | — | — | |
| SCHEMBL28627434 | 0.97 | MAOB (0.55) | — | |
| Water SCHEMBL28448011 | 0.97 | MAOB (0.55) | — | |
| SCHEMBL8428975 | 0.97 | MAOB (0.55) | — | |
| SCHEMBL23630615 | 0.97 | MAOB (0.55) | — | |
| SCHEMBL28440624 | 0.92 | MAOB (0.50) | — | |
| SCHEMBL17002705 | 0.92 | MAOB (0.50) | — | |
| SCHEMBL11256399 | 0.89 | MAOB (0.48) | — | |
| SCHEMBL28386292 | 0.89 | MAOB (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227859-B1 | NEUROPHILIN LIGANDS FOR TREATING OCULAR CONDITIONS | ALCON INC (CH) | 2006-08-09 | — | — | EP | claimed |
| EP-0777478-B1 | INHIBITORS OF ROTAMASE ENZYME ACTIVITY | GUILFORD PHARM INC (US) | 2001-11-07 | — | — | EP | claimed |
| US-20230391711-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-12-07 | — | — | US | disclosed |
| EP-4276089-A2 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | Universite De Moncton (CA) | 2023-11-15 | — | — | EP | disclosed |
| US-11760715-B2 | Modulators of lipoxygenase and cyclooxygenase enzyme activity | UNIVERSITÉ DE MONCTON (CA) | 2023-09-19 | — | — | US | disclosed |
| EP-3022206-B1 | EPHA4 INHIBITORS AS NEUROPROTECTIVE AGENTS | UNIV HONG KONG SCIENCE & TECH (HK) | 2023-07-12 | — | — | EP | disclosed |
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | disclosed |
| CN-114560888-A | Preparation method of alpha, beta-unsaturated phosphonamide compound | 北京化工大学 | 2022-05-31 | — | — | CN | disclosed |
| US-20190119194-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIVERSITE DE MONCTON (CA) | 2019-04-25 | — | — | US | disclosed |
| EP-3423429-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | Universite De Moncton (CA) | 2019-01-09 | — | — | EP | disclosed |
| US-9629830-B2 | EphA4 inhibitors as neuroprotective agents | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-04-25 | — | — | US | disclosed |
| US-20160152618-A1 | EphA4 INHIBITORS AS NEUROPROTECTIVE AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-06-02 | — | — | US | disclosed |
| EP-2838927-A2 | SULFONIUM COMPOUNDS, THEIR PREPARATION AND USE | BASF SE (DE) | 2015-02-25 | — | — | EP | disclosed |
| US-20150044509-A1 | SULFONIUM COMPOUNDS, THEIR PREPARATION AND USE | BASF SE (DE) | 2015-02-12 | — | — | US | disclosed |
| US-20140005301-A1 | SULFONIUM SULFATES, THEIR PREPARATION AND USE | BASF SE (DE) | 2014-01-02 | — | — | US | disclosed |
| EP-2678311-A1 | SULFONIUM SULFATES, THEIR PREPARATION AND USE | BASF SE (DE) | 2014-01-01 | — | — | EP | disclosed |
| WO-2013156509-A2 | SULFONIUM COMPOUNDS, THEIR PREPARATION AND USE | BASF SE (DE) | 2013-10-24 | — | — | WO | disclosed |
| WO-2012113829-A1 | SULFONIUM SULFATES, THEIR PREPARATION AND USE | BASF SE (DE) | 2012-08-30 | — | — | WO | disclosed |
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |