Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 20/20 | 0.59 |
| ▸ | FLT4 | P35916 | 20/20 | 0.59 |
| ▸ | KDR | P35968 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5966697 | 0.90 | FLT1 (0.65) | FLT1FLT4KDR | |
| SCHEMBL5966486 | 0.85 | FLT1 (0.58) | FLT1FLT4KDR | |
| SCHEMBL5966477 | 0.85 | FLT1 (0.61) | FLT1FLT4KDR | |
| Tasisulam SCHEMBL1581371 | 0.81 | FLT1 (0.62) | FLT1FLT4KDR | |
| SCHEMBL5966433 | 0.81 | FLT1 (0.62) | FLT1FLT4KDR | |
| Tasisulam SCHEMBL29376914 | 0.81 | FLT1 (0.62) | FLT1FLT4KDR | |
| SCHEMBL31487939 | 0.81 | FLT1 (0.63) | FLT1FLT4KDR | |
| Tasisulam SCHEMBL1662355 | 0.80 | FLT1 (0.61) | FLT1FLT4KDR | |
| SCHEMBL21741575 | 0.79 | FLT1 (0.60) | FLT1FLT4KDR | |
| SCHEMBL5966505 | 0.78 | FLT1 (0.63) | FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442030-B1 | THIOPENE- AMD THIAZOLESULFONAMIDES AS ANTINEOPLASTIC AGENTS | LILLY CO ELI (US) | 2006-08-30 | — | — | EP | disclosed |