⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11717074 | 0.67 | — | — | |
| SCHEMBL313188 | 0.67 | — | — | |
| Alcohol SCHEMBL28551069 | 0.63 | — | — | |
| SCHEMBL29587059 | 0.59 | — | — | |
| Alcohol SCHEMBL3924490 | 0.59 | — | — | |
| Ethylene Glycol SCHEMBL28494266 | 0.59 | — | — | |
| Methyl Alcohol SCHEMBL8575320 | 0.59 | — | — | |
| SCHEMBL589778 | 0.59 | — | — | |
| SCHEMBL8317224 | 0.59 | — | — | |
| Alcohol SCHEMBL28488370 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324257-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2012-12-04 | — | — | US | claimed |
| US-20100041719-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2010-02-18 | — | — | US | claimed |
| CN-101553476-A | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC (US) | 2009-10-07 | — | — | CN | claimed |
| US-20230263803-A1 | METHODS OF PREVENTING OR TREATING COVID-19 AND RELATED VIRAL DISEASES OR DISORDERS | KINARUS AG (CH) | 2023-08-24 | — | — | US | disclosed |
| EP-4196120-A1 | METHODS OF PREVENTING OR TREATING COVID-19 AND RELATED VIRAL DISEASES OR DISORDERS | Kinarus AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| EP-4159212-A1 | P38 KINASE INHIBITORS REDUCE DUX4 AND DOWNSTREAM GENE EXPRESSION FOR THE TREATMENT OF FSHD | Fulcrum Therapeutics, Inc. (US) | 2023-04-05 | — | — | EP | disclosed |
| US-11576916-B2 | Methods of preventing or treating ophthalmic diseases | KINARUS AG (CH) | 2023-02-14 | — | — | US | disclosed |
| US-20220175786-A1 | PHARMACEUTICAL COMBINATIONS FOR TREATING CANCER | SUPPORT-VENTURE GMBH (CH) | 2022-06-09 | — | — | US | disclosed |
| US-20220133704-A1 | P38 KINASE INHIBITORS REDUCE DUX4 AND DOWNSTREAM GENE EXPRESSION FOR THE TREATMENT OF FSHD | FULCRUM THERAPEUTICS INC (US) | 2022-05-05 | — | — | US | disclosed |
| US-11291659-B2 | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD | Fulcrum Therapeutics, Inc. (US) | 2022-04-05 | — | — | US | disclosed |
| WO-2022034031-A1 | METHODS OF PREVENTING OR TREATING COVID-19 AND RELATED VIRAL DISEASES OR DISORDERS | KINARUS AG (CH) | 2022-02-17 | — | — | WO | disclosed |
| US-5011623-A | Nonlinear optical material and nonlinear optical device | CANON KABUSHIKI KAISHA (JP) | 1991-04-30 | — | — | US | disclosed |
| US-4981614-A | COMPRISING A MIXTURE OF POLYLACTONE OR NYLON COPOLYMER AND AN ORGANIC GUEST ELECTRONEGATIVE COMPOUND; NONLINEAR OPTICAL DEVICES; FILMS FOR DISPLAYS; CRYSTAL WAVELENGTH CONVERTERS FOR LASERS | CANON KABUSHIKI KAISHA (JP) | 1991-01-01 | — | — | US | disclosed |
| US-4946261-A | Recording method and recording apparatus | CANON KABUSHIKI KAISHA (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0351832-A2 | Nonlinear optical material and nonlinear optical device | CANON KABUSHIKI KAISHA (JP) | 1990-01-24 | — | — | EP | disclosed |
| EP-0332455-A2 | Photosensitive material and image forming method | CANON KABUSHIKI KAISHA (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0308852-A2 | Solid solution | CANON KABUSHIKI KAISHA (JP) | 1989-03-29 | — | — | EP | disclosed |
| EP-0295145-A2 | Recording method and recording apparatus | CANON KABUSHIKI KAISHA (JP) | 1988-12-14 | — | — | EP | disclosed |
| EP-0284229-A1 | Nonlinear optical material and method for orientation thereof | CANON KABUSHIKI KAISHA (JP) | 1988-09-28 | — | — | EP | disclosed |
| US-4216111-A | Stable dispersions of fluorescent whitening agents of the bis-triazinylaminostilbene group in free acid form and method of preparing same | HICKSON & WELCH LIMITED (GB) | 1980-08-05 | — | — | US | disclosed |