Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 19/20 | 1.00 |
| ▸ | FPR3 | P25089 | 1/20 | 1.00 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 1.00 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 1.00 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bx 471 Free Base SCHEMBL4586646 | 1.00 | CCR1 (1.00) | CCR1FPR3GPR65GPR35PTGDR2 | |
| Bx 471 Free Base SCHEMBL4589100 | 1.00 | CCR1 (1.00) | CCR1FPR3GPR65GPR35PTGDR2 | |
| Bx 471 Free Base SCHEMBL30059128 | 1.00 | CCR1 (1.00) | CCR1FPR3GPR65GPR35PTGDR2 | |
| Bx 471 Free Base SCHEMBL29416828 | 1.00 | CCR1 (1.00) | CCR1FPR3GPR65GPR35PTGDR2 | |
| Bx 471 Free Base SCHEMBL3699446 | 0.99 | CCR1 (1.00) | CCR1FPR3GPR65GPR35PTGDR2 | |
| Bx 471 Free Base SCHEMBL30172123 | 0.99 | CCR1 (1.00) | CCR1FPR3GPR65GPR35PTGDR2 | |
| Bx 471 Free Base SCHEMBL434321 | 0.99 | CCR1 (1.00) | CCR1FPR3GPR65GPR35PTGDR2 | |
| Bx 471 Free Base SCHEMBL6949884 | 0.97 | CCR1 (0.94) | CCR1FPR3GPR65GPR35PTGDR2 | |
| Bx 471 Free Base SCHEMBL6949887 | 0.95 | CCR1 (0.91) | CCR1FPR3GPR65GPR35 | |
| SCHEMBL13035071 | 0.92 | CCR1 (0.85) | CCR1FPR3GPR65GPR35PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727526-A2 | PIPERAZINE UREA DERIVATIVES FOR THE TREATMENT OF ENDOMETRIOSIS | Schering Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | claimed |
| WO-2005079769-A2 | PIPERAZINE DERIVATIVES FOR THE TREATMENT OF ENDOMETRIOSIS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-09-01 | — | — | WO | claimed |
| EP-1727526-A2 | PIPERAZINE UREA DERIVATIVES FOR THE TREATMENT OF ENDOMETRIOSIS | Schering Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| EP-1713483-A1 | CHEMOKINE INHIBITING PIPERAZINE DERIVATIVES AND THEIR USE TO TREAT MULTIPLE MYELOMA | Schering Aktiengesellschaft (DE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005079769-A2 | PIPERAZINE DERIVATIVES FOR THE TREATMENT OF ENDOMETRIOSIS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-09-01 | — | — | WO | disclosed |
| WO-2005077372-A1 | CHEMOKINE INHIBITING PIPERAZINE DERIVATIVES AND THEIR USE TO TREAT MULTIPLE MYELOMA | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-08-25 | — | — | WO | disclosed |