Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 17/20 | 0.67 |
| ▸ | FPR3 | P25089 | 1/20 | 0.49 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | ACTR2 | P61160 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4588914 | 1.00 | CCR1 (0.67) | CCR1FPR3GPR65GPR35MAPK11 | |
| SCHEMBL4588909 | 1.00 | CCR1 (0.67) | CCR1FPR3GPR65GPR35MAPK11 | |
| SCHEMBL4588918 | 1.00 | CCR1 (0.67) | CCR1FPR3GPR65GPR35MAPK11 | |
| SCHEMBL5059083 | 0.92 | CCR1 (0.64) | CCR1FPR3GPR65GPR35MAPK11 | |
| SCHEMBL5059079 | 0.92 | CCR1 (0.64) | CCR1FPR3GPR65GPR35MAPK11 | |
| SCHEMBL5059080 | 0.92 | CCR1 (0.64) | CCR1FPR3GPR65GPR35MAPK11 | |
| SCHEMBL5064105 | 0.91 | CCR1 (0.68) | CCR1FPR3GPR65GPR35MAPK11 | |
| SCHEMBL5064099 | 0.91 | CCR1 (0.68) | CCR1FPR3GPR65GPR35MAPK11 | |
| SCHEMBL5064109 | 0.91 | CCR1 (0.68) | CCR1FPR3GPR65GPR35MAPK11 | |
| SCHEMBL4588748 | 0.90 | CCR1 (0.78) | CCR1FPR3GPR65GPR35PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727526-A2 | PIPERAZINE UREA DERIVATIVES FOR THE TREATMENT OF ENDOMETRIOSIS | Schering Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005079769-A2 | PIPERAZINE DERIVATIVES FOR THE TREATMENT OF ENDOMETRIOSIS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-09-01 | — | — | WO | disclosed |