Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29173690 | 1.00 | KMT2A (0.41) | KMT2AFABP5FABP7EPHX2MDM2 | |
| SCHEMBL28124455 | 0.93 | KMT2A (0.42) | KMT2AFABP5FABP7EPHX2MDM2 | |
| SCHEMBL16060617 | 0.93 | KMT2A (0.42) | KMT2AFABP5FABP7EPHX2MDM2 | |
| SCHEMBL28124396 | 0.92 | KMT2A (0.43) | KMT2AFABP5FABP7EPHX2MDM2 | |
| SCHEMBL17079656 | 0.92 | KMT2A (0.43) | KMT2AFABP5FABP7EPHX2MDM2 | |
| SCHEMBL16061106 | 0.91 | KMT2A (0.45) | KMT2AFABP5FABP7EPHX2MDM2 | |
| SCHEMBL28124397 | 0.91 | KMT2A (0.45) | KMT2AFABP5FABP7EPHX2MDM2 | |
| SCHEMBL14054298 | 0.91 | KMT2A (0.41) | KMT2AFABP5FABP7EPHX2MDM2 | |
| SCHEMBL28125253 | 0.89 | CA1 (0.37) | KMT2AFABP5FABP7EPHX2MDM2 | |
| SCHEMBL17316183 | 0.89 | CA1 (0.37) | KMT2AFABP5FABP7EPHX2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390760-B | FAK-targeting compound and preparation method and application thereof | 北京师范大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-112390760-A | FAK-targeting compound and preparation method and application thereof | 北京师范大学 | 2021-02-23 | — | — | CN | disclosed |
| EP-1232183-B1 | PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LAB (US) | 2006-01-18 | — | — | EP | disclosed |
| US-6753408-B1 | DRUGS USED FOR THERAPY | ABBVIE INC. | 2004-06-22 | — | — | US | disclosed |
| EP-1232183-A2 | PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LABORATORIES (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001038347-A2 | PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LABORATORIES (US) | 2001-05-31 | — | — | WO | disclosed |