SCHEMBL5973473

SCHEMBL5973473

CCOC(=O)COc1ccc(SCC(O)C=Cc2ccc(C(F)(F)F)cc2)cc1C

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.55
PPARA Q07869 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5973476 1.00 PPARD (0.55) PPARDPPARA
SCHEMBL5973470 1.00 PPARD (0.55) PPARDPPARA
SCHEMBL7019136 0.90 PPARD (0.67) PPARDPPARA
SCHEMBL3696342 0.89 PPARD (0.56) PPARDPPARA
SCHEMBL3696347 0.89 PPARD (0.56) PPARDPPARA
SCHEMBL3696344 0.89 PPARD (0.56) PPARDPPARA
SCHEMBL7017165 0.86 PPARD (0.51) PPARDPPARA
SCHEMBL7015790 0.84 PPARD (0.47) PPARDPPARA
SCHEMBL14355030 0.83 PPARD (0.48) PPARDPPARA
SCHEMBL10151835 0.83 PPARD (0.51) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1667964-A2 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS JANSSEN PHARMACEUTICA N.V. (BE) 2006-06-14 EP disclosed
WO-2005042478-A2 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS JANSSEN PHARMACEUTICA, N.V. (BE) 2005-05-12 WO disclosed