Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.68 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.68 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.68 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.68 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.68 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.68 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5973782 | 0.99 | GRIN1 (0.67) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL5973556 | 0.85 | GRIN1 (0.69) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL5973847 | 0.85 | GRIN1 (0.58) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| Bromide SCHEMBL5973260 | 0.84 | GRIN1 (0.69) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL5973378 | 0.84 | GRIN1 (0.57) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL5974170 | 0.83 | GRIN1 (0.67) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| Bromide SCHEMBL5973959 | 0.83 | GRIN1 (0.66) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| Bromide SCHEMBL5973842 | 0.83 | GRIN1 (0.66) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL5974209 | 0.82 | GRIN1 (0.64) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| Bromide SCHEMBL5973774 | 0.81 | GRIN1 (0.63) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934326-B1 | SUBSTITUTED AMINOALKANE PHOSPHONIC ACIDS | NOVARTIS AG (CH) | 2006-05-03 | — | — | EP | claimed |
| EP-0934326-B1 | SUBSTITUTED AMINOALKANE PHOSPHONIC ACIDS | NOVARTIS AG (CH) | 2006-05-03 | — | — | EP | disclosed |