SCHEMBL59739

SCHEMBL59739

CCCCC[CH]CCCCC

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.53
THRB P10828 1/20 0.50
FAAH O00519 2/20 0.46
TRPV1 Q8NER1 2/20 0.46
DNM1 Q05193 3/20 0.44
LMNA P02545 1/20 0.43
ALDH1A1 P00352 2/20 0.42
EP300 Q09472 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25177176 0.96 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25176521 0.96 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25171009 0.96 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25171010 0.96 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25170219 0.96 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25173853 0.96 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25174145 0.96 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25171013 0.96 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25171005 0.96 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25174128 0.96 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4532 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024613-B2 Composition containing a polymer and an additive École Polytechnique Fédérale De Lausanne (EPFL)—Technology Transfer Office (TTO) (CH) 2024-07-02 US claimed
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN claimed
US-20240150344-A1 PROCESS FOR PRODUCING ACYLOXYMETHYL ESTERS OF (4S)-(4-CYANO-2-METHOXYPHENYL)-5-ETHOXY-2,8-DIMETHYL-1,4-DIHYDRO-1,6-NAPHTHYRIDIN-3-CARBOXYLIC ACID BAYER AKTIENGESELLSCHAFT (DE) 2024-05-09 US claimed
CN-116120198-B Lipid compound with glycerol skeleton, lipid carrier based on lipid compound, nucleic acid lipid nanoparticle composition and pharmaceutical preparation 苏州科锐迈德生物医药科技有限公司 2024-03-15 CN claimed
CN-116891465-A N-substituted quinolinone compounds, preparation method and application thereof 苏州旺山旺水生物医药有限公司 2023-10-17 CN claimed
WO-2023186023-A1 N-SUBSTITUTED QUINOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 苏州旺山旺水生物医药股份有限公司 2023-10-05 WO claimed
WO-2023179499-A1 LIPID COMPOUND HAVING GLYCEROL SKELETON, LIPID CARRIER BASED ON LIPID COMPOUND, NUCLEIC ACID LIPID NANOPARTICLE COMPOSITION, AND PHARMACEUTICAL PREPARATION 苏州科锐迈德生物医药科技有限公司 2023-09-28 WO claimed
US-11753635-B2 Methods and systems and related compositions for mixtures separation with a solid matrix CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-09-12 US claimed
WO-2023057810-A1 CHEMOLYTIC UPGRADING OF LOW-VALUE MACROMOLECULE FEEDSTOCKS TO HIGHER-VALUE FUELS AND CHEMICALS Aduro Clean Technologies (CA) 2023-04-13 WO claimed
US-RE49118-E1 Material for organic electroluminescence device and electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2022-06-28 US claimed
EP-0445862-A2 N-(4-piperidinyl)(dihydrobenzofuran or dihydro-2H-benzopyran)carboxamide derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1991-09-11 EP claimed
EP-0426717-A1 OPTICAL MEMORY. RIEDEL DE HAEN AG (DE) 1991-05-15 EP claimed
EP-0389037-A1 N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1990-09-26 EP claimed
WO-1990001480-A1 OPTICAL MEMORY RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1990-02-22 WO claimed
US-4837309-A IMPROVED COLORFASTNESS AND LIGHTFASTNESS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1989-06-06 US claimed
EP-0244595-A2 Dihydropyridine derivatives, process for their preparation and their use as pharmaceutical compounds Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1987-11-11 EP claimed
EP-0125781-B1 PEROXYGEN COMPOUNDS Interox Chemicals Limited (GB) 1987-08-12 EP claimed
EP-0101023-B1 PROCESS FOR PREPARING 2-CARBAMOYLOXYALKYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND INTERMEDIATES USEFUL FOR THE PROCESS BANYU PHARMACEUTICAL CO., LTD. (JP) 1987-07-29 EP claimed
EP-0121847-B1 2,2-DIMETHYL-3-(2-HALOVINYL)CYCLOPROPANE CARBOXYLATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BAYER AG (DE) 1987-01-14 EP claimed
US-4541944-A BLEACHES, LAUNDRY INTEROX CHEMICALS LIMITED (GB) 1985-09-17 US claimed