Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | PDE2A | O00408 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | CD99 | P14209 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.48 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.48 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.48 |
| ▸ | GAPDH | P04406 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5974629 | 1.00 | ADA (0.55) | ADAADORA3ADORA2AADORA1PDE2A | |
| SCHEMBL16926953 | 1.00 | ADA (0.55) | ADAADORA3ADORA2AADORA1PDE2A | |
| SCHEMBL27734444 | 1.00 | ADA (0.55) | ADAADORA3ADORA2AADORA1PDE2A | |
| Nebularine SCHEMBL29799158 | 0.89 | ADA (0.65) | ADAADORA3ADORA2AADORA1KDM4E | |
| Nebularine SCHEMBL10666450 | 0.89 | ADA (0.65) | ADAADORA3ADORA2AADORA1KDM4E | |
| Nebularine SCHEMBL742475 | 0.89 | ADA (0.65) | ADAADORA3ADORA2AADORA1KDM4E | |
| Nebularine SCHEMBL9644429 | 0.89 | ADA (0.65) | ADAADORA3ADORA2AADORA1KDM4E | |
| Nebularine SCHEMBL745560 | 0.89 | ADA (0.65) | ADAADORA3ADORA2AADORA1KDM4E | |
| Nebularine SCHEMBL29362246 | 0.89 | ADA (0.65) | ADAADORA3ADORA2AADORA1KDM4E | |
| Nebularine SCHEMBL27552329 | 0.89 | ADA (0.65) | ADAADORA3ADORA2AADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024567-A1 | MODIFIED CYCLIC DINUCLEOTIDE COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2021-01-28 | — | — | US | disclosed |
| WO-2019185476-A1 | MODIFIED CYCLIC DINUCLEOTIDE COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-10-03 | — | — | WO | disclosed |
| EP-1261350-B1 | METHODS FOR SYNTHESIZING 2-CHLORO-9-(2-DEOXY-2-FLUORO-BETA-D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE | SOUTHERN RES INST (US) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024567-A1 | MODIFIED CYCLIC DINUCLEOTIDE COMPOUNDS | STING1, CGAS, IRF3 | ADA 345/4885ADORA3 363/4885ADORA2A 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.