Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.78 |
| ▸ | CHRM2 | P08172 | 17/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 17/20 | 0.77 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.59 |
| ▸ | TACR1 | P25103 | 2/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.59 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5979030 | 1.00 | CHRM3 (0.78) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL5978037 | 1.00 | CHRM3 (0.78) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Trifluoroacetic Acid SCHEMBL1234071 | 0.94 | CHRM3 (0.70) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Trifluoroacetic Acid SCHEMBL1233366 | 0.94 | CHRM3 (0.70) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Trifluoroacetic Acid SCHEMBL1234786 | 0.94 | CHRM3 (0.70) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL5975943 | 0.90 | CHRM3 (0.81) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL5979295 | 0.90 | CHRM3 (0.81) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL4636670 | 0.90 | CHRM3 (0.80) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL4637780 | 0.90 | CHRM3 (0.80) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL5978728 | 0.90 | CHRM3 (0.68) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353919-B1 | NOVEL QUINUCLIDINE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | ALMIRALL PRODESFARMA AG (CH) | 2006-07-26 | — | — | EP | claimed |