Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.68 |
| ▸ | ACE | P12821 | 3/20 | 0.68 |
| ▸ | MMEL1 | Q495T6 | 8/20 | 0.67 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21572793 | 1.00 | MME (0.68) | MMEACEMMEL1CTSSCTSK | |
| SCHEMBL30889 | 1.00 | MME (0.68) | MMEACEMMEL1CTSSCTSK | |
| SCHEMBL3877643 | 1.00 | MME (0.68) | MMEACEMMEL1CTSSCTSK | |
| SCHEMBL1908539 | 1.00 | MME (0.68) | MMEACEMMEL1CTSSCTSK | |
| SCHEMBL29046 | 1.00 | MME (0.68) | MMEACEMMEL1CTSSCTSK | |
| SCHEMBL29983 | 1.00 | MME (0.68) | MMEACEMMEL1CTSSCTSK | |
| SCHEMBL3867666 | 1.00 | MME (0.68) | MMEACEMMEL1CTSSCTSK | |
| SCHEMBL13566634 | 1.00 | MME (0.68) | MMEACEMMEL1CTSSCTSK | |
| SCHEMBL1232351 | 0.99 | MME (0.67) | MMEACEMMEL1CTSSCTSK | |
| SCHEMBL1231233 | 0.99 | MME (0.67) | MMEACEMMEL1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715601-B | Sakuba starter method for preparing calcium | 华中药业股份有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-118516422-A | Method for synthesizing Sha Kuba koji intermediate by biocatalysis | 江苏海洋大学 | 2024-08-20 | — | — | CN | claimed |
| CN-115677521-B | Preparation method of high-purity Sha Kuba koji calcium | 迪嘉药业集团股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-116751135-A | Preparation method of Sakuba/valsartan sodium | 苏州东瑞制药有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-116715601-A | Preparation method of sabadica | 华中药业股份有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-115677521-A | Preparation method of high-purity Shakuba kojie calcium | 迪嘉药业集团股份有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-113816871-A | LCZ696 impurity and preparation method thereof | 江苏开放大学（江苏城市职业学院） | 2021-12-21 | — | — | CN | claimed |
| CN-112641773-A | Composition containing heterocyclic compound and use thereof | 黄泳华 | 2021-04-13 | — | — | CN | claimed |
| CN-110845349-B | Purification method of Sacubitril valsartan sodium intermediate | 株洲千金药业股份有限公司 | 2020-11-24 | — | — | CN | claimed |
| CN-111265518-A | Composition containing a mixture of biphenyl derivatives and uses thereof | 黄泳华 | 2020-06-12 | — | — | CN | claimed |
| CN-110845349-A | Purification method of Sacubitril valsartan sodium intermediate | 株洲千金药业股份有限公司 | 2020-02-28 | — | — | CN | claimed |
| CN-110818581-A | Post-treatment method of Sacubitril valsartan sodium intermediate | 株洲千金药业股份有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-120904081-A | Method for continuously preparing (2R, 4S) -5- (biphenyl-4-yl) -4- [ (tert-butoxycarbonyl) amino ] -2-methyl pentanoic acid | 苏州第四制药厂有限公司 | 2025-11-07 | — | — | CN | disclosed |
| CN-120904081-A | Method for continuously preparing (2R, 4S) -5- (biphenyl-4-yl) -4- [ (tert-butoxycarbonyl) amino ] -2-methyl pentanoic acid | 苏州第四制药厂有限公司 | 2025-11-07 | — | — | CN | disclosed |
| CN-116715601-B | Sakuba starter method for preparing calcium | 华中药业股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-119613294-A | Preparation method of sabatier starter intermediate | 浙江达弗氏医药科技有限公司 | 2025-03-14 | — | — | CN | disclosed |
| EP-1903027-A1 | Process for preparing biaryl substituted 4-amino-butyric acid or derivatives thereof and their use in the production of NEP inhibitors | Novartis AG (CH) | 2008-03-26 | — | — | EP | disclosed |
| EP-1903027-A1 | Process for preparing biaryl substituted 4-amino-butyric acid or derivatives thereof and their use in the production of NEP inhibitors | Novartis AG (CH) | 2008-03-26 | — | — | EP | disclosed |
| WO-2008031567-A1 | PROCESS FOR PREPARING BIARYL SUBSTITUTED 4-AMINO-BUTYRIC ACID OR DERIVATIVES THEREOF AND THEIR USE IN THE PRODUCTION OF NEP INHIBITORS | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008031567-A1 | PROCESS FOR PREPARING BIARYL SUBSTITUTED 4-AMINO-BUTYRIC ACID OR DERIVATIVES THEREOF AND THEIR USE IN THE PRODUCTION OF NEP INHIBITORS | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |