Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NRP1 | O14786 | 5/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4852562 | 0.99 | PTGS1 (0.38) | PTGS1PTGS2MAPTALDH1A1MAPK1 | |
| SCHEMBL4888444 | 0.91 | PTGS1 (0.37) | PTGS1PTGS2MAPTALDH1A1MAPK1 | |
| SCHEMBL5982205 | 0.91 | PTGS1 (0.37) | PTGS1PTGS2MAPTPKLRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4858674 | 0.90 | PTGS1 (0.36) | PTGS1PTGS2MAPTPKLRSMN1; SMN2 | |
| SCHEMBL5982479 | 0.90 | PTGS1 (0.39) | PTGS1PTGS2TAAR1BCHEACHE | |
| SCHEMBL5983138 | 0.90 | PTGS1 (0.39) | PTGS1PTGS2MAPTALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4859445 | 0.89 | PTGS1 (0.39) | PTGS1PTGS2TAAR1BCHEACHE | |
| Hydrochloric Acid SCHEMBL4853654 | 0.89 | PTGS1 (0.39) | PTGS1PTGS2MAPTALDH1A1MAPK1 | |
| SCHEMBL5982519 | 0.88 | BCHE (0.39) | PTGS1PTGS2TAAR1BCHEACHE | |
| SCHEMBL4855552 | 0.88 | PTGS1 (0.37) | PTGS1PTGS2MAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138533-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-11-21 | — | — | US | claimed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |