Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.52 |
| ▸ | ADH1B | P00325 | 1/20 | 0.52 |
| ▸ | ADH1C | P00326 | 1/20 | 0.52 |
| ▸ | ADH1A | P07327 | 1/20 | 0.52 |
| ▸ | ADH4 | P08319 | 1/20 | 0.52 |
| ▸ | ADH7 | P40394 | 1/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopentane SCHEMBL28710079 | 0.95 | TSHR (0.68) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL22915556 | 0.91 | TSHR (0.93) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL22535934 | 0.91 | TSHR (0.93) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL20746342 | 0.91 | TSHR (0.93) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL23929261 | 0.91 | TSHR (0.93) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL23929263 | 0.91 | TSHR (0.93) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL23929270 | 0.91 | TSHR (0.93) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL23929276 | 0.91 | TSHR (0.93) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL21611680 | 0.91 | TSHR (0.93) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL22288098 | 0.91 | TSHR (0.93) | TSHRALDH1A1EPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067697-B2 | Cationic liposomes for gene transfer | VANDERBILT UNIVERSITY (US) | 2006-06-27 | — | — | US | disclosed |
| US-20060057194-A1 | Cationic liposomes for gene transfer | GAO XIANG | 2006-03-16 | — | — | US | disclosed |
| US-7002042-B2 | Cationic liposomes for gene transfer | VANDERBILT UNIVERSITY (US) | 2006-02-21 | — | — | US | disclosed |
| US-6656498-B1 | Cationic liposomes for gene transfer | VANDERBILT UNIVERSITY | 2003-12-02 | — | — | US | disclosed |
| US-20030049310-A1 | Cationic liposomes for gene transfer | VANDERBILT UNIVERSITY | 2003-03-13 | — | — | US | disclosed |
| WO-2000030444-A1 | CATIONIC LIPOSOMES FOR GENE TRANSFER | VANDERBILT UNIVERSITY (US) | 2000-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060057194-A1 | Cationic liposomes for gene transfer | LCLAT1, LPCAT3, LPCAT1 | TSHR 3205/4885ALDH1A1 4443/4885EPHX1 3358/4885 |
| US-20030049310-A1 | Cationic liposomes for gene transfer | LCLAT1, LPCAT3, LPCAT1 | TSHR 3205/4885ALDH1A1 4443/4885EPHX1 3358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.