Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958006 | 1.00 | S1PR2 (0.53) | S1PR2S1PR1S1PR3DPP4GRIK1 | |
| SCHEMBL3967288 | 1.00 | S1PR2 (0.53) | S1PR2S1PR1S1PR3DPP4GRIK1 | |
| SCHEMBL5983634 | 1.00 | S1PR2 (0.53) | S1PR2S1PR1S1PR3DPP4GRIK1 | |
| SCHEMBL3962574 | 1.00 | S1PR2 (0.53) | S1PR2S1PR1S1PR3DPP4GRIK1 | |
| SCHEMBL4002242 | 0.89 | S1PR2 (0.52) | S1PR2S1PR1GRIK1MMP2MMP3 | |
| SCHEMBL3967381 | 0.89 | S1PR2 (0.52) | S1PR2S1PR1GRIK1MMP2MMP3 | |
| SCHEMBL3962307 | 0.89 | S1PR2 (0.52) | S1PR2S1PR1GRIK1MMP2MMP3 | |
| SCHEMBL3965958 | 0.89 | S1PR2 (0.52) | S1PR2S1PR1GRIK1MMP2MMP3 | |
| SCHEMBL5983830 | 0.88 | S1PR2 (0.52) | S1PR2S1PR1S1PR3DPP4GRIK1 | |
| SCHEMBL3997989 | 0.88 | S1PR2 (0.52) | S1PR2S1PR1S1PR3DPP4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670452-A2 | METHOD OF USE OF AMINOACIDS HAVING AFFINITY FOR THE A2D PROTEIN | Warner-Lambert Company LLC (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030184-A2 | THERAPEUTIC BETA AMINOACIDS | WARNER-LAMBERT COMPANY LLC (US) | 2005-04-07 | — | — | WO | disclosed |