Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 10/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2677733 | 1.00 | ESR1 (0.56) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL10599506 | 0.91 | ESR1 (0.63) | ESR1LMNAPGRSLC6A3ESR2 | |
| SCHEMBL10631994 | 0.91 | ESR1 (0.63) | ESR1LMNAPGRSLC6A3ESR2 | |
| SCHEMBL10605315 | 0.90 | ESR1 (0.59) | ESR1LMNASMN1; SMN2ADORA3ATM | |
| SCHEMBL10631976 | 0.90 | ESR1 (0.59) | ESR1LMNASMN1; SMN2ADORA3ATM | |
| SCHEMBL10632047 | 0.87 | STS (0.65) | ESR1PGRSLC6A3ADORA3AR | |
| SCHEMBL8647143 | 0.87 | STS (0.65) | ESR1PGRSLC6A3ADORA3AR | |
| SCHEMBL10602626 | 0.87 | STS (0.65) | ESR1PGRSLC6A3ADORA3AR | |
| SCHEMBL10629851 | 0.87 | STS (0.65) | ESR1PGRSLC6A3ADORA3AR | |
| SCHEMBL9597951 | 0.84 | ESR1 (0.62) | ESR1LMNASMN1; SMN2PGRSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025394-A1 | Estradiol-related compounds and methods of use as anti-tumor agents | HO SHUK-MEI | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025394-A1 | Estradiol-related compounds and methods of use as anti-tumor agents | ESR2, ESR1, ESRRB | ESR1 2/4885LMNA 2577/4885SMN1; SMN2 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.