Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.56 |
| ▸ | PPARA | Q07869 | 15/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977594 | 1.00 | PPARG (0.56) | PPARGPPARAHDAC1HDAC3HDAC7 | |
| SCHEMBL3974335 | 0.99 | PPARG (0.55) | PPARGPPARAHDAC1HDAC3HDAC7 | |
| SCHEMBL3972713 | 0.98 | PPARG (0.56) | PPARGPPARAHDAC1HDAC3HDAC7 | |
| SCHEMBL3974597 | 0.96 | PPARG (0.58) | PPARGPPARAHDAC1HDAC3HDAC7 | |
| SCHEMBL3974353 | 0.94 | PPARG (0.54) | PPARGPPARAHDAC1HDAC3HDAC7 | |
| SCHEMBL3974606 | 0.93 | PPARG (0.64) | PPARGPPARAHDAC1 | |
| SCHEMBL5984622 | 0.93 | PPARG (0.64) | PPARGPPARAHDAC1 | |
| SCHEMBL3974226 | 0.91 | PPARG (0.64) | PPARGPPARA | |
| SCHEMBL3980861 | 0.90 | PPARG (0.56) | PPARGPPARAHDAC1HDAC3HDAC7 | |
| SCHEMBL3978007 | 0.89 | PPARG (0.67) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | claimed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | claimed |