Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983788 | 1.00 | FOLH1 (0.45) | FOLH1SLC1A3SLC1A2SLC1A1MME | |
| SCHEMBL1199396 | 1.00 | FOLH1 (0.45) | FOLH1SLC1A3SLC1A2SLC1A1MME | |
| SCHEMBL1199395 | 1.00 | FOLH1 (0.45) | FOLH1SLC1A3SLC1A2SLC1A1MME | |
| SCHEMBL1716335 | 0.84 | SLC1A3 (0.58) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL8314295 | 0.84 | SLC1A3 (0.58) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL1954749 | 0.84 | SLC1A3 (0.58) | FOLH1SLC1A3SLC1A2SLC1A1MME | |
| SCHEMBL1198437 | 0.83 | CHRM1 (0.52) | FOLH1SLC1A3SLC1A2SLC1A1MME | |
| SCHEMBL1198439 | 0.83 | CHRM1 (0.52) | FOLH1SLC1A3SLC1A2SLC1A1MME | |
| SCHEMBL21052490 | 0.83 | SLC1A3 (0.52) | FOLH1SLC1A3SLC1A2SLC1A1MME | |
| SCHEMBL11319029 | 0.82 | SLC1A3 (0.56) | FOLH1SLC1A3SLC1A2SLC1A1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670452-A2 | METHOD OF USE OF AMINOACIDS HAVING AFFINITY FOR THE A2D PROTEIN | Warner-Lambert Company LLC (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030184-A2 | THERAPEUTIC BETA AMINOACIDS | WARNER-LAMBERT COMPANY LLC (US) | 2005-04-07 | — | — | WO | disclosed |