⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983485 | 0.93 | TSHR (0.54) | — | |
| SCHEMBL28738004 | 0.86 | TSHR (0.63) | — | |
| SCHEMBL222525 | 0.84 | — | — | |
| SCHEMBL9161783 | 0.79 | — | — | |
| Lithium Ion SCHEMBL17456558 | 0.78 | RECQL (0.58) | — | |
| SCHEMBL2750585 | 0.78 | RECQL (0.65) | — | |
| Lithium Ion SCHEMBL17456418 | 0.78 | RECQL (0.65) | — | |
| Ethylenediamine SCHEMBL21296506 | 0.76 | RECQL (0.88) | — | |
| Lithium Ion SCHEMBL17456412 | 0.76 | RECQL (0.70) | — | |
| Lithium Ion SCHEMBL17456492 | 0.76 | RECQL (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652621-A | MALEIMIDE WITH SULFONATE OR SULFATE GROUP, DRILLING FLUID DISPERSANT | NIPPON ZEON CO., LTD. (JP) | 1987-03-24 | — | — | US | claimed |
| CN-109996541-A | N- acyl amino acid compounds and its application method | 普利安特治疗公司 | 2019-07-09 | — | — | CN | disclosed |
| US-9840515-B2 | Protein kinase D inhibitors | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2017-12-12 | — | — | US | disclosed |
| US-20140045821-A1 | PROTEIN KINASE D INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2014-02-13 | — | — | US | disclosed |
| WO-2012078859-A2 | PROTEIN KINASE D INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2012-06-14 | — | — | WO | disclosed |
| EP-1691780-A2 | GENE DELIVERY MEDIATED BY LIPOSOME-DNA COMPLEX WITH CLEAVABLE PEG SURFACE MODIFICATION | ALZA CORPORATION (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005051351-A2 | GENE DELIVERY MEDIATED BY LIPOSOME-DNA COMPLEX WITH CLEAVABLE PEG SURFACE MODIFICATION | ALZA CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |
| US-6849270-B2 | Releasable linkage and compositions containing same | ALZA CORPORATION (US) | 2005-02-01 | — | — | US | disclosed |
| EP-1465599-A1 | LIPOSOME COMPOSITION FOR DELIVERY OF NUCLEIC ACID | ALZA Corporation (US) | 2004-10-13 | — | — | EP | disclosed |
| US-20030211079-A1 | Releasable linkage and compositions containing same | ALZA CORPORATION | 2003-11-13 | — | — | US | disclosed |
| WO-2003053409-A1 | LIPOSOME COMPOSITION FOR DELIVERY OF NUCLEIC ACID | ALZA CORPORATION (US) | 2003-07-03 | — | — | WO | disclosed |
| EP-1173221-A2 | RELEASABLE LINKAGE AND COMPOSITIONS CONTAINING SAME | Alza Corporation (US) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064483-A2 | RELEASABLE LINKAGE AND COMPOSITIONS CONTAINING SAME | ALZA CORPORATION (US) | 2000-11-02 | — | — | WO | disclosed |
| EP-0628860-B1 | New type of modified gelatin and its use in a DTR material | AGFA GEVAERT NV (BE) | 1997-10-15 | — | — | EP | disclosed |
| US-5536817-A | DIFFUSION TRANSFER REVERSAL | AGFA-GEVAERT, N.V. (BE) | 1996-07-16 | — | — | US | disclosed |
| US-5474885-A | Hydrophilic photographic diffusion transfer reversal material containing gelatin modified by sulfate, sulfonate, phosphate, or phosphonate groups, for lithographic printing plates | AGFA-GEVAERT, N.V. (BE) | 1995-12-12 | — | — | US | disclosed |
| EP-0628860-A1 | New type of modified gelatin and its use in a DTR material | AGFA-GEVAERT N.V. (BE) | 1994-12-14 | — | — | EP | disclosed |
| US-4652621-A | MALEIMIDE WITH SULFONATE OR SULFATE GROUP, DRILLING FLUID DISPERSANT | NIPPON ZEON CO., LTD. (JP) | 1987-03-24 | — | — | US | disclosed |