⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17111088 | 0.73 | — | — | |
| SCHEMBL9191979 | 0.65 | — | — | |
| SCHEMBL13929441 | 0.60 | — | — | |
| SCHEMBL20099403 | 0.60 | — | — | |
| SCHEMBL10658621 | 0.60 | — | — | |
| Benzene SCHEMBL6537104 | 0.59 | — | — | |
| SCHEMBL22265094 | 0.59 | — | — | |
| SCHEMBL23829645 | 0.57 | — | — | |
| SCHEMBL20271921 | 0.57 | — | — | |
| SCHEMBL29379795 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290434-A | Spiropiperidine derivative containing alpha-methylene-gamma-butyrolactone, preparation method and application thereof | 南开大学 | 2024-07-05 | — | — | CN | claimed |
| CN-110759873-B | 4, 5-dihydrothiazole carboxylic acid derivatives containing sulfonyl hydrazine structure, and preparation method and application thereof | 天津中医药大学 | 2023-12-19 | — | — | CN | claimed |
| CN-118290434-A | Spiropiperidine derivative containing alpha-methylene-gamma-butyrolactone, preparation method and application thereof | 南开大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-103442566-A | Compounds for treatment of cancer | GTX INC | 2013-12-11 | — | — | CN | disclosed |
| CN-101573357-A | Indole compound | TAKEDA PHARMACEUTICAL (JP) | 2009-11-04 | — | — | CN | disclosed |
| EP-1656360-A1 | THIAZOLINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-17 | — | — | EP | disclosed |
| WO-2004113309-A1 | THIAZOLINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-12-29 | — | — | WO | disclosed |
| CN-1313855-A | Inhibitors of alpha4Betal mediated cell adhesion alpha Beta | UPJOHN CO (US) | 2001-09-19 | — | — | CN | disclosed |