Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.58 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 12/20 | 0.45 |
| ▸ | HTR1D | P28221 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK16 | Q00536 | 1/20 | 0.44 |
| ▸ | WNT1 | P04628 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964809 | 0.86 | CHRNA7 (0.62) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL1964044 | 0.81 | CHRNA7 (0.67) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL2791404 | 0.80 | CHRNA7 (0.61) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL1964726 | 0.80 | CHRNA7 (0.67) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL1967272 | 0.80 | CHRNA7 (0.72) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL12315166 | 0.79 | CHRNA7 (0.64) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL1965456 | 0.78 | CHRNA7 (0.65) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL1963671 | 0.78 | CHRNA7 (0.70) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| Formic Acid SCHEMBL1967216 | 0.78 | CHRNA7 (0.57) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL2788242 | 0.77 | CHRNA7 (0.66) | CHRNA7HTR3AGSK3BDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735306-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005092890-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |