Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 17/20 | 0.59 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PTPRF | P10586 | 1/20 | 0.42 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670491 | 0.86 | PTPN1 (0.75) | PTPN1SIRT3TTR | |
| SCHEMBL3978232 | 0.85 | PTPN1 (0.61) | PTPN1TTRPTPRFPTPRAPTPN7 | |
| SCHEMBL3971675 | 0.80 | PTPN1 (0.53) | PTPN1TTR | |
| SCHEMBL3973525 | 0.80 | PTPN1 (0.48) | PTPN1SIRT3TTR | |
| SCHEMBL3971361 | 0.77 | PTPN1 (0.54) | PTPN1SIRT3TTR | |
| SCHEMBL4672732 | 0.76 | PTPN1 (0.78) | PTPN1SIRT3TTR | |
| SCHEMBL6336686 | 0.75 | PTPN1 (0.70) | PTPN1SIRT3TTRPTPRFPTPRA | |
| SCHEMBL6336688 | 0.75 | PTPN1 (0.70) | PTPN1SIRT3TTRPTPRFPTPRA | |
| SCHEMBL7506554 | 0.75 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL3978636 | 0.75 | PTPN1 (0.47) | PTPN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |