Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646450 | 0.81 | FFAR1 (0.65) | SMN1; SMN2ALDH1A1FFAR1KMT2AMEN1 | |
| SCHEMBL1170312 | 0.78 | FFAR1 (0.68) | SMN1; SMN2ALDH1A1FFAR1KMT2ASTAT3 | |
| SCHEMBL8746034 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1FFAR1KMT2ASTAT3 | |
| Hydrochloric Acid SCHEMBL3043801 | 0.77 | FFAR1 (0.65) | SMN1; SMN2ALDH1A1FFAR1KMT2ASTAT3 | |
| SCHEMBL7835806 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1FFAR1KMT2ASTAT3 | |
| SCHEMBL3735703 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1FFAR1KMT2ACA12 | |
| SCHEMBL11212870 | 0.75 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11217371 | 0.75 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL1395735 | 0.75 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL11212921 | 0.75 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060135483-A1 | Oxygen/nitrogen heterocycle inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2006-06-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135483-A1 | Oxygen/nitrogen heterocycle inhibitors of tyrosine phosphatases | PTPRO, PTPRG, PTPN1 | SMN1; SMN2 1565/4885ALDH1A1 1227/4885FFAR1 3633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.