Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988386 | 0.74 | NR4A2 (0.39) | HDAC1HDAC6ALDH1A1HDAC2NPSR1 | |
| SCHEMBL3973520 | 0.71 | HDAC1 (0.41) | CNR1CNR2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL5988096 | 0.69 | CNR1 (0.40) | CNR1CNR2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL4785214 | 0.62 | NCEH1 (0.38) | HDAC1HDAC6ALDH1A1HDAC2MEN1 | |
| SCHEMBL3979138 | 0.60 | ROCK1 (0.42) | HDAC1HDAC6MAPTHTT | |
| SCHEMBL17324721 | 0.58 | POLB (0.79) | CNR1CNR2ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL30049353 | 0.58 | POLB (0.79) | CNR1CNR2ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL3971810 | 0.58 | HDAC1 (0.50) | CNR1CNR2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL3973124 | 0.58 | HTT (0.54) | CNR1CNR2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL2078365 | 0.58 | CNR2 (1.00) | CNR1CNR2L3MBTL1MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | claimed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | claimed |