Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5987987 | 0.99 | HTR2A (0.55) | HTR2ATAAR1HTR1AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL20563992 | 0.78 | TAAR1 (0.50) | HTR2ATAAR1HTR2CHTR2B | |
| SCHEMBL48210 | 0.76 | PDE4A (0.43) | HTR2AHTR1AHTR2C | |
| SCHEMBL4580168 | 0.75 | MCL1 (0.55) | — | |
| SCHEMBL5987458 | 0.73 | CYP3A4 (0.57) | — | |
| SCHEMBL29425260 | 0.73 | HTR2A (1.00) | HTR2ATAAR1HTR1AHTR2CHTR2B | |
| SCHEMBL398581 | 0.73 | HTR2A (1.00) | HTR2ATAAR1HTR1AHTR2CHTR2B | |
| SCHEMBL398580 | 0.73 | HTR2A (1.00) | HTR2ATAAR1HTR1AHTR2CHTR2B | |
| SCHEMBL21167302 | 0.73 | CA12 (0.43) | — | |
| SCHEMBL5308098 | 0.72 | HTR2A (0.81) | HTR2ATAAR1HTR1AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045545-B1 | Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists | ELI LILLY AND COMPANY (US) | 2006-05-16 | — | — | US | disclosed |
| EP-1149085-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000044737-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |