Sugi Predict

Sugi Predict / Compounds / SCHEMBL5989286

SCHEMBL5989286

SCHEMBL5989286

CCc1ccc(OC(C)CCOc2ccc(CCC(=O)O)c(C)c2)c(C(=O)c2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 20/20 1.00
▸ PPARD Q03181 20/20 1.00
▸ PPARA Q07869 17/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5403316 0.96 PPARG (0.92) PPARGPPARDPPARA
SCHEMBL5387383 0.94 PPARG (0.89) PPARGPPARDPPARA
SCHEMBL5990153 0.94 PPARG (0.89) PPARGPPARDPPARA
SCHEMBL5990313 0.93 PPARG (0.87) PPARGPPARDPPARA
SCHEMBL5990310 0.93 PPARG (0.87) PPARGPPARDPPARA
SCHEMBL5394122 0.93 PPARG (0.86) PPARGPPARDPPARA
SCHEMBL5991697 0.93 PPARG (0.86) PPARGPPARDPPARA
SCHEMBL5990351 0.92 PPARG (0.84) PPARGPPARDPPARA
SCHEMBL5392595 0.92 PPARG (0.84) PPARGPPARDPPARA
SCHEMBL5392755 0.91 PPARG (0.84) PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060257987-A1 Ppar modulators ELI LILLY AND COMPANY 2006-11-16 — — US claimed
US-20060257987-A1 Ppar modulators ELI LILLY AND COMPANY 2006-11-16 — — US disclosed
EP-1660428-A1 PPAR MODULATORS ELI LILLY AND COMPANY (US) 2006-05-31 — — EP disclosed
WO-2005019151-A1 PPAR MODULATORS ELI LILLY AND COMPANY (US) 2005-03-03 — — WO disclosed