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SCHEMBL5989718

SCHEMBL5989718

CCc1ccc(OC(C)CCOc2ccc(CCC(=O)O)c(C)c2)c(Oc2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 20/20 1.00
▸ PPARD Q03181 20/20 1.00
▸ PPARA Q07869 17/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5989710 1.00 PPARG (1.00) PPARGPPARDPPARA
SCHEMBL5990059 0.94 PPARG (0.88) PPARGPPARDPPARA
SCHEMBL5990066 0.94 PPARG (0.88) PPARGPPARDPPARA
SCHEMBL5990126 0.93 PPARG (0.86) PPARGPPARDPPARA
SCHEMBL5990129 0.93 PPARG (0.86) PPARGPPARDPPARA
SCHEMBL5989109 0.92 PPARG (0.85) PPARGPPARDPPARA
SCHEMBL5989104 0.92 PPARG (0.85) PPARGPPARDPPARA
SCHEMBL5989362 0.90 PPARG (0.83) PPARGPPARDPPARA
SCHEMBL5989370 0.90 PPARG (0.83) PPARGPPARDPPARA
SCHEMBL5989535 0.89 PPARG (0.80) PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060257987-A1 Ppar modulators ELI LILLY AND COMPANY 2006-11-16 — — US claimed
US-20060257987-A1 Ppar modulators ELI LILLY AND COMPANY 2006-11-16 — — US disclosed
EP-1660428-A1 PPAR MODULATORS ELI LILLY AND COMPANY (US) 2006-05-31 — — EP disclosed
WO-2005019151-A1 PPAR MODULATORS ELI LILLY AND COMPANY (US) 2005-03-03 — — WO disclosed
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