Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.53 |
| ▸ | PPARD | Q03181 | 7/20 | 0.53 |
| ▸ | PPARA | Q07869 | 7/20 | 0.53 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5992130 | 1.00 | PPARG (0.53) | PPARGPPARDPPARAKCNQ3KCNQ2 | |
| SCHEMBL5990526 | 1.00 | PPARG (0.53) | PPARGPPARDPPARAKCNQ3KCNQ2 | |
| SCHEMBL5991150 | 0.83 | PPARG (0.51) | PPARGPPARDPPARAL3MBTL1HTT | |
| SCHEMBL5989975 | 0.83 | PPARG (0.51) | PPARGPPARDPPARAL3MBTL1HTT | |
| SCHEMBL5989981 | 0.83 | PPARG (0.51) | PPARGPPARDPPARAL3MBTL1HTT | |
| SCHEMBL5989417 | 0.83 | PPARG (0.58) | PPARGPPARDPPARAKCNQ3KCNQ2 | |
| SCHEMBL5989413 | 0.83 | PPARG (0.58) | PPARGPPARDPPARAKCNQ3KCNQ2 | |
| SCHEMBL5991304 | 0.82 | PPARG (0.53) | PPARGPPARDPPARAKCNQ3KCNQ2 | |
| SCHEMBL5991311 | 0.82 | PPARG (0.53) | PPARGPPARDPPARAKCNQ3KCNQ2 | |
| SCHEMBL5989606 | 0.79 | KCNQ3 (0.44) | PPARGPPARDPPARAKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |