Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.64 |
| ▸ | PPARD | Q03181 | 15/20 | 0.64 |
| ▸ | PPARA | Q07869 | 13/20 | 0.64 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5989905 | 1.00 | PPARG (0.64) | PPARGPPARDPPARACCNB2CCNE2 | |
| SCHEMBL5990495 | 0.86 | PPARG (0.65) | PPARGPPARDPPARACCNB2CCNE2 | |
| SCHEMBL5991546 | 0.86 | PPARG (0.61) | PPARGPPARDPPARACCNB2CCNE2 | |
| SCHEMBL5989831 | 0.84 | PPARG (0.63) | PPARGPPARDPPARACCNB2CCNE2 | |
| SCHEMBL5992887 | 0.84 | PPARG (0.63) | PPARGPPARDPPARACCNB2CCNE2 | |
| SCHEMBL5989827 | 0.84 | PPARG (0.63) | PPARGPPARDPPARACCNB2CCNE2 | |
| SCHEMBL6054868 | 0.82 | PPARG (0.78) | PPARGPPARDPPARA | |
| SCHEMBL6054863 | 0.82 | PPARG (0.78) | PPARGPPARDPPARA | |
| SCHEMBL5991764 | 0.82 | IRAK4 (0.49) | PPARGPPARDPPARACCNB2CCNE2 | |
| SCHEMBL5989804 | 0.82 | PPARG (0.76) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |