Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5991109 | 0.94 | STAT3 (0.43) | STAT3CA12CA9CA1ALDH1A1 | |
| SCHEMBL4303888 | 0.89 | CA12 (0.44) | STAT3CA12CA9CA1ALDH1A1 | |
| SCHEMBL5474740 | 0.89 | CA12 (0.44) | STAT3CA12CA9CA1ALDH1A1 | |
| SCHEMBL5477848 | 0.89 | CA12 (0.44) | STAT3CA12CA9CA1ALDH1A1 | |
| SCHEMBL28577424 | 0.88 | CA12 (0.43) | STAT3CA12CA9CA1ALDH1A1 | |
| SCHEMBL4921650 | 0.88 | STAT3 (0.41) | STAT3CA12CA9CA1ALDH1A1 | |
| SCHEMBL4921663 | 0.88 | STAT3 (0.41) | STAT3CA12CA9CA1ALDH1A1 | |
| SCHEMBL4929727 | 0.88 | STAT3 (0.41) | STAT3CA12CA9CA1ALDH1A1 | |
| SCHEMBL3940922 | 0.86 | STAT3 (0.40) | STAT3CA12CA9CA1ALDH1A1 | |
| SCHEMBL3940918 | 0.86 | STAT3 (0.40) | STAT3CA12CA9CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |
| EP-1370547-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002081464-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2002-10-17 | — | — | WO | disclosed |