Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.73 |
| ▸ | PPARD | Q03181 | 12/20 | 0.73 |
| ▸ | PPARA | Q07869 | 12/20 | 0.73 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990106 | 1.00 | PPARG (0.73) | PPARGPPARDPPARAFFAR4FFAR1 | |
| SCHEMBL5989723 | 0.91 | PPARG (0.73) | PPARGPPARDPPARAFFAR4FFAR1 | |
| SCHEMBL5989726 | 0.91 | PPARG (0.73) | PPARGPPARDPPARAFFAR4FFAR1 | |
| SCHEMBL5989519 | 0.91 | PPARG (0.65) | PPARGPPARDPPARAFFAR4FFAR1 | |
| SCHEMBL5989516 | 0.91 | PPARG (0.65) | PPARGPPARDPPARAFFAR4FFAR1 | |
| SCHEMBL5991581 | 0.90 | PPARG (0.67) | PPARGPPARDPPARAFFAR4FFAR1 | |
| SCHEMBL5991590 | 0.90 | PPARG (0.67) | PPARGPPARDPPARAFFAR4FFAR1 | |
| SCHEMBL5411425 | 0.90 | PPARG (0.77) | PPARGPPARDPPARAFFAR4FFAR1 | |
| SCHEMBL5411420 | 0.90 | PPARG (0.77) | PPARGPPARDPPARAFFAR4FFAR1 | |
| SCHEMBL5991879 | 0.89 | PPARG (0.75) | PPARGPPARDPPARAFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | claimed |
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |